Skeletal muscle relaxant effect of Chonemorpha macrophylla in experimental animals
نویسندگان
چکیده
منابع مشابه
Screening of Skeletal Muscle Relaxant Activity of Plant Vicia Faba
The study was designed to investigate the skeletal muscle relaxant activity of vicia faba (400mg/kg, p.o) by using rota rod apparatus. Experiments were carried out on albino mice and the animals were randomly allotted to the different control, test and standard (diazepam 4mg/kg, p.o) groups. The methanolic extract significantly reduced the fall off time (4.33sec) in comparision with the fall of...
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It is not clear whether the muscle wasting commonly observed in hyperthyroidism is due to alteration in the rate of protein synthesis or degradation. The effect of experimental hyperthyroidism on skeletal-muscle proteolysis in the rat was studied by measuring alanine and tyrosine release from isolated skeletal muscles in vitro and 3-methyl-histidine excretion in vivo. Alanine release from the i...
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The mouse LD50 assay is routinely used for potency testing of botulinum toxins. Unfortunately, this test is associated with severe pain and distress in animals and requires large quantities of mice. Here we used cocultures of spinal cord and muscle tissue as an alternative for probing botulinum toxins. Cocultures were prepared from mouse embryonic tissue (C57/BL6J) and cultured for 24-27 days. ...
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The mouse LD50 assay is routinely used for potency testing of botulinum toxins. Unfortunately, this test is associated with severe pain and distress in animals and requires large quantities of mice. Here we used cocultures of spinal cord and muscle tissue as an alternative for probing botulinum toxins. Cocultures were prepared from mouse embryonic tissue (C57/BL6J) and cultured for 24-27 days. ...
متن کاملFetal programming of skeletal muscle development in ruminant animals.
Enhancing skeletal muscle growth is crucial for animal agriculture because skeletal muscle provides meat for human consumption. An increasing body of evidence shows that the level of maternal nutrition alters fetal skeletal muscle development, with long-term effects on offspring growth and performance. Fetal skeletal muscle development mainly involves myogenesis (i.e., muscle cell development),...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2005
ISSN: 0253-7613
DOI: 10.4103/0253-7613.15113